Baby born with rare disorder thrives after getting personalized gene editing treatment

Though it may be a while before similar personalized treatments are available for others, doctors hope the technology can someday help millions who have been left behind by genetic medicine because their diseases are so rare.

Deadly U.S. plane crashes in 2025: Timeline

Since the beginning of 2025, at least 188 people have died in 60 U.S. aviation incidents.

Suspect in custody after Gov. Shapiro's home set on fire with family inside

Pennsylvania State Police are investigating an act of arson carried out at the Governor's Residence in Harrisburg while Gov. Josh Shapiro and his family were sleeping inside.

Driver escapes after massive tree falls onto SUV in Chester County

Video captured a massive ash tree crashing down onto a Chester County roadway, crushing a car and shocking fellow drivers.

Sudiksha Konanki missing: What we know so far

It's been a week since Sudiksha Konanki, a University of Pittsburgh college student, went missing in the Dominican Republic. Here's everything we know about what happened.

Philadelphia man wanted for murder of pregnant girlfriend caught in Atlanta

Police say the Philadelphia man had been on the run for nearly four years after shooting his pregnant girlfriend in the head multiple times. An expired car tag helped bring him to justice in Atlanta.

Officer killed after a gunman took hostages at a Pennsylvania hospital

Authorities say a gunman entered a Pennsylvania hospital’s intensive care unit and took staff members hostage before he was killed by police in a shootout that also left an officer dead.

2 women shot after fight near Eagles Super Bowl Parade; 1 man charged

The Philadelphia Police Department is investigating a shooting that happened near the Eagles Super Bowl Parade that left two women injured and a man has been taken into custody.